Histochemical study of the skeletal muscle in children with chronic renal failure in dialysis treatment

Arquivos de Neuro-Psiquiatria

Lucila Bizari Fernandes Do Prado²  Gilmar Fernandes Do Prado¹  Acary Souza Bulle Oliveira¹  Beny Schmidt¹  JoÃo TomÁs De Abreu Carvalhaes¹ 

[1],Universidade Federal de São Paulo Escola Paulista de Medicina Departamento de Pediatria

关键词: chronic renal failure;    dialysis;    muscular biopsy;    uremia;    insuficiência renal crônica;    diálise;    biópsia muscular;    uremia;   

DOI  :  10.1590/S0004-282X1998000300006

来源: SciELO

【 摘 要 】

Among the modifications occurring in the uremic organism, in addition to the consequences of dialysis, myophathy and peripheral neuropathy are very significant. Children are particularly affected, as their growth and development are jeopardized. Histochemistry of muscular biopsy was used to study eighteen children with end-stage renal failure under dialysis during a ten-month period. According to our results, the skeletal muscular tissue presented the following types of alterations: atrophy, type grouping, lipidosis, glycogen depletion and mitochondrial proliferation.

【 授权许可】

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