Hemangioblastoma of the posterior fossa: the role of multimodality treatment

Arquivos de Neuro-Psiquiatria

Alvaro E. Georg²  L. Dade Lunsford¹  Douglas Kondziolka¹  John C. Flickinger¹  Ann Maitz¹ 

[1],Universidade Federal da BahiaSalvador BA ,Brasil

关键词: hemangioblastoma;    treatment;    radiosurgery;    radiotherapy;    hemangioblastoma;    tratamento;    radiocirurgia;    radioterapia;   

DOI  :  10.1590/S0004-282X1997000200016

来源: SciELO

【 摘 要 】

The authors made a review of a series of patients with hemangioblastomas of the posterior fossa treated between 1973 and 1993. A total of 32 patients were analyzed with 24 patients receiving resection, 8 patients receiving radiosurgery and 2 patients receiving conventional radiotherapy. The mortality in the patients with a resection was considered acceptable with 2 deaths (8%) and with a morbidity of 3 patients (12.5%). A review of the literature suggests that conventional radiotherapy with high doses (45-60 Gy) may have a role in the post-operative control of hemangioblastomas and in some cases could be employed even before the resection in order to facilitate the surgery. The radiosurgical treatment is regarded like adjuvant. Poor results were obtained with radiosurgery in large tumors where low doses (less than 20 Gy) were used. Because of the rarity and complexity of these tumors, mainly when associated with von Hippel-Lindau disease, a multicenter study could be useful with the assessment of the optimal utilization and combination of these treatment modalities.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License