Polymerase chain reaction in the diagnosis of tuberculous meningitis: preliminary report

Arquivos de Neuro-Psiquiatria

L.r. Machado¹  J.a. Livramento¹  S.p. Bydlowski¹  I. Bendit¹  L.m. Bravo¹  A. Spina-frança¹ 

[1] ,Universidade de São Paulo Faculdade de Medicina Departamento de Neurologia

关键词: PCR;    CSF;    tuberculous meningitis;    meningoencephalitis;    PCR;    LCR;    meningoencefalite tuberculosa;    meningoencefalites;   

DOI  :  10.1590/S0004-282X1994000300029

来源: SciELO

【 摘 要 】

In this preliminary report the results of PCR for detection of DNA sequences (65 KDa antigen) of Mycobacterium tuberculosis in CSF samples from 20 patients are registered. In 10 patients there were clinical and laboratory findings suggesting the diagnosis of tuberculous meningitis (test group). In the other 10 patients, clinical and laboratory findings suggested meningitis or meningo-encephalitis from other etiologies (control group). In 7 patients from the test group antigenic DNA sequences of Mycobacterium tuberculosis were found in CSF by PCR; positive results were not registered in the control group.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License