Liver resection: 10-year experience from a single Institution

Arquivos de Gastroenterologia

Julio Cezar Uili Coelho²  Christiano Marlo Paggi Claus¹  Tiago Noguchi Machuca²  Wagner Herbert Sobottka²  Carolina Gomes Gonçalves¹ 

[1] ,Federal University of Parana Hospital de Clínicas Digestive Surgery Division

关键词: Liver;    neoplasms;    Neoplasm metastasis;    Carcinoma;    hepatocellular;    Hepatectomy;    Risk factors;    Neoplasias hepáticas;    Metástase neoplásica;    Carcinoma hepatocelular;    Hepatectomia;    Fatores de risco;   

DOI  :  10.1590/S0004-28032004000400006

来源: SciELO

【 摘 要 】

BACKGROUND: Liver resection constitutes the main treatment of most liver primary neoplasms and selected cases of metastatic tumors. However, this procedure is associated with significant morbidity and mortality rates. AIM: To analyze our experience with liver resections over a period of 10 years to determine the morbidity, mortality and risk factors of hepatectomy. PATIENTS AND METHODS: Retrospective review of medical records of patients who underwent liver resection from January 1994 to March 2003. RESULTS: Eighty-three (41 women and 42 men) patients underwent liver resection during the study period, with a mean age of 52.7 years (range 13-82 years). Metastatic colorectal carcinoma and hepatocellular carcinoma were the main indications for hepatic resection, with 36 and 19 patients, respectively. Extended and major resections were performed in 20.4% and 40.9% of the patients, respectively. Blood transfusion was needed in 38.5% of the operations. Overall morbidity was 44.5%. Life-threatening complications occurred in 22.8% of cases and the most common were pneumonia, hepatic failure, intraabdominal collection and intraabdominal bleeding. Among minor complications (30%), the most common were biliary leakage and pleural effusion. Size of the tumor and blood transfusion were associated with major complications (P = 0.0185 and P = 0.0141, respectively). Operative mortality was 8.4% and risk factors related to mortality were increased age and use of vascular exclusion (P = 0.0395 and P = 0.0404, respectively). Median hospital stay was 6.7 days. CONCLUSION: Liver resections can be performed with low mortality and acceptable morbidity rates. Blood transfusion may be reduced by employing meticulous technique and, whenever indicated, vascular exclusion.

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