Corneal melanosis successfully treated using topical mitomycin-C and alcohol corneal epitheliectomy: a 3-year follow-up case report

Arquivos Brasileiros de Oftalmologia

Mehmet Balcı¹  Ramazan Yağcı¹  Emre Güler¹  Hacer Haltaş¹  Rahmi Duman¹  İbrahim F. Hepşen¹ 

关键词: Epiteliectomia;    Álcool;    Cicatrização da córnea;    Melanose córnea;    Melanoma maligno;    Mitomicina-C;    Epitheliectomy;    Alcohol;    Corneal haze;    Corneal melanosis;    Malignant melanoma;    Mitomycin-C;   

DOI  :  10.5935/0004-2749.20150066

来源: SciELO

【 摘 要 】

ABSTRACTWe report a case of primary acquired corneal melanosis without atypia associated with corneal haze in a patient with a history of limbal malignant melanoma and the effect of mitomycin-C. A 75-year-old woman with a history of limbal malignant melanoma presented with loss of vision in right eye. Corneal examination showed a patchy melanotic pigmentation with a central haze. Topical mitomycin-C improved visual acuity and corneal haze. However, the pigmented lesions persisted, and they were removed with alcohol corneal epitheliectomy. Histopathological examination demonstrated primary acquired melanosis without atypia. The lesions were successfully removed, and there were no recurrences during the follow-up period of 36 months. The association of conjunctival and corneal melanosis without atypia is a rare condition. In addition, co-existence of central corneal haze and melanosis may decrease visual acuity. Topical mitomycin-C and alcohol corneal epitheliectomy can be useful treatments in this condition.

【 授权许可】

CC BY   
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