Phacoemulsification and foldable acrylic IOL implantation in children with treated retinoblastoma

Arquivos Brasileiros de Oftalmologia

Marcia Beatriz Tartarella²  Gloria Fátima Britez-colombi²  Marcia Motono¹  Martha Motono Chojniak¹  Joao Borges Fortes Filho¹  Rubens Belfort Jr.² 

[1],Universidade Federal de São Paulo Department of Ophthalmology São Paulo SP ,Brazil

关键词: Retinoblastoma;    Retinoblastoma;    Retinal neoplasms;    Cataract;    Eye enucleation;    Radiation injuries;    Radiotherapy;    Lens implantation;    intraocular;    Humans;    Child;    Retinoblastoma;    Retinoblastoma;    Neoplasisas da retina;    Catarata;    Enucleação ocular;    Lesões por radiação;    Radioterapia;    Implante de lente intraocular;    Humanos;    Criança;   

DOI  :  10.1590/S0004-27492012000500011

来源: SciELO

【 摘 要 】

PURPOSE: To study the results of cataract surgery in children with radiation-induced cataract after treatment for retinoblastoma. METHODS: Retrospective interventional case series. Six consecutive patients diagnosed with secondary cataracts due to radiation therapy for retinoblastoma. Intervention: Phacoemulsification and foldable acrylic intraocular lens implantation. Outcomes measu- red: Visual acuity, binocular indirect ophthalmoscopy and slit-lamp biomicroscopy. Aspirated lens material and aqueous humor samples were collected during surgery. RESULTS: Six uniocular children between 3 to 5 years of age at time of surgery were studied. The mean time interval between radiotherapy and cataract diagnosis was 22.3 months. The mean follow-up after surgery was 17.2 months (range: 12 to 23 months). All eyes achieved a clear visual axis after surgery allowing monitoring of the tumor status. None developed recurrence or retinoblastoma dissemination. Histopathological analysis of the aspired material showed no tumoral cells in all samples. All patients improved vision after cataract surgery. CONCLUSIONS: Phacoemulsification with acrylic intraocular lens implantation seems to be a safe, feasible, and effective method for the removal of radiation-induced cataracts in patients with treated retinoblastoma.

【 授权许可】

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