Lack of papillomavirus (HPV) in pterygia of a Brazilian sample

Arquivos Brasileiros de Oftalmologia

Silvana Artioli Schellini²  Erika Hoyama¹  Claudia Akemi Shiratori¹  Regina Hitomi Sakamoto¹  João Manuel Grisi Candeias¹ 

[1],Universidade Estadual Paulista Julio de Mesquita Filho Faculdade de Medicina de Botucatu Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e PescoçoBotucatu SP ,Brasil

关键词: Papillomavirus;    Pterygium;    Polymerase chain reaction;    HPV DNA probes;    Papilomavirus;    Pterígio;    Reação em cadeia da polimerase;    Sondas DNA HPV;   

DOI  :  10.1590/S0004-27492006000400012

来源: SciELO

【 摘 要 】

PURPOSE: Because the influence of papillomavirus (HPV) in pterygium pathogenesis is controversial, the aim of this study was to identify whether it is present in the pterygia lesions in our region. METHODS: Thirty-six patients with unilateral primary pterygia were submitted to excision of pterygia and a sample of normal conjunctiva. Tissues were submitted to polymerase chain reaction (PCR) evaluation for papillomavirus DNA detection. RESULTS: We were unable to detect any HPV DNA in all studied specimens. CONCLUSION: According to our results papillomarivus is not important for pterygium formation.

【 授权许可】

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