Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity

Anais da Academia Brasileira de Ciências

Eduardo A.a. Pinheiro¹  Josiwander M. Carvalho¹  Diellem C.p. Dos Santos¹  André O. Feitosa¹  Patrícia S.b. Marinho¹  Giselle Maria S.p. Guilhon¹  Lourivaldo S. Santos¹  Afonso L.d. De Souza¹  Andrey M.r. Marinho¹ 

关键词: chemical constituents;    antimicrobial assay;    Aspergillus;    Bauhinia guianensis;    constituintes químicos;    ensaio antimicrobiano;    Aspergillus;    Bauhinia guianensis;   

DOI  :  10.1590/0001-3765201395512

来源: SciELO

【 摘 要 】

The present work reports the isolation of five compounds from Aspergillus sp EJC08 isolated as endophytic from Bauhinia guianensis, a tipical plant of the Amazon. The compounds ergosterol (1), ergosterol peroxide (2), mevalolactone (3), monomethylsulochrin (4) and trypacidin A (5) were isolated by chromatographic procedures and identified by spectral methods of 1D and 2D NMR and MS. Compounds 3, 4 and 5 were tested against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus and showed good activity.

【 授权许可】

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