Antimutagenic and antirecombinagenic activities of noni fruit juice in somatic cells of Drosophila melanogaster

Anais da Academia Brasileira de Ciências

Leonardo P. Franchi¹  Nilza N. Guimaraes¹  Laise R. De Andrade¹  Heloisa H.r. De Andrade¹  Mauricio Lehmann¹  Rafael R. Dihl¹  Kenya S. Cunha¹ 

关键词: antigenotoxicity;    doxorrubicin;    mitomycin C;    SMART;    noni juice;    antigenotoxicidade;    doxorrubicina;    mitomicina C;    SMART;    suco de noni;   

DOI  :  10.1590/S0001-37652013000200008

来源: SciELO

【 摘 要 】

Noni, a Hawaiian name for the fruit of Morinda citrifolia L., is a traditional medicinal plant from Polynesia widely used for the treatment of many diseases including arthritis, diabetes, asthma, hypertension and cancer. Here, a commercial noni juice (TNJ) was evaluated for its protective activities against the lesions induced by mitomycin C (MMC) and doxorrubicin (DXR) using the Somatic Mutation and Recombination Test (SMART) in Drosophila melanogaster. Three-day-old larvae, trans-heterozygous for two genetic markers (mwh and flr3

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