Design and application of oral colon administration system

Journal of Enzyme Inhibition and Medicinal Chemistry

Hao Cheng¹  Gangliang Huang¹  Shiyu Huang¹ 

[1] Chongqing Key Laboratory of Green Synthesis and Application, Active Carbohydrate Research Institute, Chongqing Normal University, Chongqing, Chin;

关键词: Oral colon administration system;    design;    application;   

DOI  :  10.1080/14756366.2019.1655406

来源: publisher

【 摘 要 】

Oral colon administration system has become a new method to treat intestinal diseases. The implementation of colon drug delivery system is restricted by many aspects, including physical and chemical properties, drug delivery mode, gastrointestinal physiological factors, and so on. Delivery methods to overcome these challenges revolve around the mechanisms of drug delivery, including the use of rational dosage forms to avoid the complex pH environment, and the prevention of drug release and absorption in the upper digestive tract.

【 授权许可】

CC BY