期刊论文详细信息
Molecules | |
Improvement of a Critical Intermediate Step in the Synthesis of a Nitroxide-Based Spin-Labeled Deoxythymidine Analog | |
Jeannine H. Powell1  Edward M. Johnson1  | |
[1] Department of Basic Pharmaceutical Sciences, West Virginia University School of Pharmacy, P. O. Box 9530, Morgantown, West Virginia, USA | |
关键词: Nitroxide; spin label; reduction; carboxylic acid; alcohol; anhydride; | |
DOI : 10.3390/51201244 | |
来源: mdpi | |
【 摘 要 】
Methods to reduce the carboxylic acid moiety in 3-carboxy-2,2,5,5-tetramethylpyrrolin-1-oxyl to an alcohol as an intermediate toward the corresponding aldehyde have been explored and an improved method has been developed.
【 授权许可】
CC BY
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202003190061099ZK.pdf | 67KB | download |