Synthesis of Platinum Complexes from N-Benzyl-1,3-Propane-diamine Derivatives, Potential Antineoplastic Agents

Molecules

Mauro Vieira de Almeida¹  Ana Paula Soares Fontes¹  Richard Nilton Berg¹  Eloi Teixeira César²  Emanoel de Castro Antunes Felໜio¹ 

[1] Departamento de Química, Universidade Federal de Juiz de Fora, 36036-330, Juiz de Fora-MG, Brazil.;Colégio de Aplicação João XXIII, Juiz de Fora-MG, Brazil.

关键词: Platinum(II) complexes;    N-benzyl 1;    3-propanediamine;    anticancer agents;   

DOI  :  10.3390/70400405

来源: mdpi

【 摘 要 】

This work describes the synthesis of seven new platinum complexes having N-benzyl 1,3-propanediamine derivatives as ligands. They were prepared by the reaction of K₂[PtCl₄] with the appropriate ligand in water. These complexes are analogs of cisplatin, and are potential antineoplastic agents.

【 授权许可】

Unknown   
© 2002 by MDPI (http://www.mdpi.org).