Reverse Phase Thin Layer Chromatography of Aminoal-kanethiosulfuric Acids, Mercaptoalkanamines and Aminoalkyl Disulfides

International Journal of Molecular Sciences

Maria das Gra๺s Cardoso³  David Lee Nelson¹  Antônia Tavares do Amaral²  Cust༽io Donizete dos Santos³  Alcilene de Abreu Pereira³ 

[1] Departamento de Alimentos, Faculdade de Farmácia, Universidade Federal de Minas Gerais, 30180-112 Belo Horizonte, MG, Brazil.;Departamento de Química Teórica, Instituto de Química, Universidade de São Paulo, São Paulo, SP, Brazil Tel.: [phone]; Fax: [phone]; E-mail:;Departamento de Química, Universidade Federal de Lavras, CP 37, CEP 37200-000 Lavras, MG, Brazil

关键词: aminoalkanethiosulfates;    mercaptoalkanamines;    aminoalkyl disulfides;    thin layer chromatography;    log P;   

DOI  :  10.3390/i3070755

来源: mdpi

【 摘 要 】

The experimental Rm values for a series of aminoalkanethiosulfuric acids, mercaptoalkanamines and aminoalkyl disulfides were determined by reverse phase thin layer chromatography.  The Rm values were determined for various concentrations of methanol:water and the correlation obtained was extrapolated to 100% water. These values permitted the calculation of the log P values for each substance. The log P values obtained by this method were compared with those obtained using the shake-flask method and by theoretical calculations utilizing fragment constants.

【 授权许可】

CC BY   
© 2002 by MDPI (http://www.mdpi.org).