Synthesis of Novel Quinazoline Derivatives via Pyrimidine ortho-Quinodimethane

Molecules

R. Chioua¹  F. Benabdelouahab¹  M. Chioua²  R. Martínez-Alvarez² 

[1] Département de Chimie, Université Abdelmalek Essaâdi, Faculté des Sciences, B.P 2121, Tétouan, Morocco. Tel. [phone], Fax [phone].;Departamento de Química Orgánica I, Facultad de Ciencias Químicas, Universidad Complutense, E-28040, Spain. Tel. [phone], Fax [phone], E-mail

关键词: [4+2] Cycloaddition;    Diels-Alder adduct;    dimethyl 2;    4-diphenylquinazoline dicarboxylate.;   

DOI  :  10.3390/70700507

来源: mdpi

【 摘 要 】

The [4+2] cycloaddition between 2,4-diphenylpyrimidine ortho-quinodimethane and dimethyl acetylenedicarboxylate leads to 2,4-diphenylquinazoline-6,7-dicarboxylate (6). 2,4-Diphenylfuro[3,4-g]quinazoline-6,8-dione (7) is also obtained by basic hydrolysis of compound 6, followed by the closure of the resulting diacid in acetic anhydride.

【 授权许可】

Unknown   
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