Molecules | |
Synthesis and Characterization of New 3,5-Dinaphthyl Substituted 2-Pyrazolines and Study of Their Antimicrobial Activity | |
Davood Azarifar1  | |
关键词: Chalcones; (Naphthalene-/substituted naphthalene-1-yl)-2-pyrazolines; Aryl substituted pyrazolines; Pyrazolines; Antimicrobial activity; Heterocyclics; | |
DOI : 10.3390/71200885 | |
来源: mdpi | |
【 摘 要 】
A number of chalcones were prepared by condensing either 1‑acetylnaphthalene or substituted 1-acetylnaphthalenes with 1-naphthaldehyde or 4‑dimethylamino-1-naphthaldehyde in ethanolic NaOH solutions. These chalcones were immediately reacted with hydrazine hydrochloride, phenyl hydrazine and semicarbazide hydrochloride in the presence of dry acetic acid to obtain the corresponding 2‑pyrazolines. The synthesised heterocycles were characterized on the basis of their chemical properties and spectroscopic data. These compounds were tested for antimicrobial activity against a variety of test organisms:
【 授权许可】
Unknown
© 2002 by MDPI (http://www.mdpi.org).
【 预 览 】
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RO202003190060755ZK.pdf | 396KB | download |