Synthesis of 2-(5-Nitropyrid-2-yl)-3-(4-substitutedphenyl)amino-isoxazol-5(2H)-ones and Their Rearrangements to Imidazo[1,2-a]- pyridines and Indoles with Triethylamine

Molecules

J. Khalafy¹  D. Setamdideh² 

[1] id="af1-molecules-07-00907">Chemistry Department, Urmia University, Urmia 57154, Iran. Fax: [phone]

关键词: Isoxazolones;    Base induced rearrangement;    Imidazopyridines;    Indoles;   

DOI  :  10.3390/71200907

来源: mdpi

【 摘 要 】

3-(4-Substitutedphenyl)aminoisoxazol-5(2H)-ones, substituted on nitrogen with a nitropyridine group, react with triethylamine to give imidazo[1,2-a]pyridines and indoles. With 4-bromophenyl and 4-methylphenyl group substituents only imidazopyridines are formed, but the 4-methoxyphenyl derivative gave a 3:1 mixture of the corresponding imidazo[1,2-a]pyridine and 2-pyridylaminoindole, respectively.

【 授权许可】

Unknown   
© 2002 by MDPI (http://www.mdpi.org).