Investigations into the Use of a Polyfluorooctanol as an Auxiliary Component for an Aldol Reaction

Molecules

Jason Eames¹ 

[1] Department of Chemistry, Queen Mary, University of London, London E1 4NS, UK

关键词: Aldol Reaction;    Carbon-Carbon Bond Formation;    Selective Extraction;   

DOI  :  10.3390/90500266

来源: mdpi

【 摘 要 】

Results are reported on the efficiency of polyfluorooctanol as a perfluorousauxiliary component in the aldol reaction between the enolate derived frompolyfluorooctyl acetate and 2-fluorobenzaldehyde. Reduction of the correspondingpolyfluoro β-hydroxy ester with Super Hydride^® gave the required 1,3-diol in good yield.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.