The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis

Molecules

Ayman W. Erian¹  Sherif M. Sherif¹ 

[1] ¹Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt ²National Organization for Drug Control and Research (NODCAR), P.O. Box 29, Cairo, Egypt

关键词: α-Haloketones;    annelated heterocycles;    oxygen nucleophiles;    nitrogen nucleophiles;    sulfur nucleophiles;    carbon nucleophiles;   

DOI  :  10.3390/81100793

来源: mdpi

【 摘 要 】

The molecular structures and spectral properties of α-haloketones as well as their syntheses are analyzed and reviewed. Their reactivity towards oxygen, nitrogen, and sulfur nucleophiles, carboxylic acids, carbon nucleophiles, alkenes, and alkynes are discussed.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.