5,5’-Biindole

Molbank

Ramiro Quintanilla-Licea¹  Juan F. Colunga-Valladares¹  Adolfo Caballero-Quintero¹  Noemí Waksman¹  Ricardo Gomez-Flores¹  Cristina Rodríguez-Padilla¹ 

[1] ¹Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Pedro de Alba s/n, Cd. Universitaria, San Nicolás de los Garza, Nuevo León, México

关键词: Indoloquinolizine;    Antitumor activity;    Teuber’s reaction;    Indole synthesis;    1H-NMR;    13C-NMR;   

DOI  :  10.3390/M474

来源: mdpi

【 摘 要 】

Synthesis of 5,5’-biindole was carried out by the Madelung indole reaction. Under strong basic conditions and high temperatures (350 ºC), N,N’-bis-formyl-o-tolidine underwent cyclization to produce high amounts of the dimeric indole. Full and unambiguous assignments of all 1H- and 13C-NMR resonances of indole and 5,5’-biindole in DMSO-d6 are also reported.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.