Facile Preparation of Peracetates and Per-3-bromobenzoates of α-Mono- and Disaccharides

Molecules

Zerong (Daniel) Wang¹  MahfuzaMatin² 

[1] id="af1-molecules-10-01325">Department of Chemistry, School of Sciences and Computer Engineering, University of Houston-Clear Lake, 2700 Bay Area Boulevard, Houston, TX 77058, USA Tel. [phone], Fax [phone]

关键词: α-Galactose;    α-glucose;    α-mannose;    lactose;    mechanochemical mixing;   

DOI  :  10.3390/10101325

来源: mdpi

【 摘 要 】

A simple and convenient method for the preparation of fully acetylated and (3-bromo)benzoylated α-monosaccharides and disaccharides through vigorous mechanical mixing of solid reactants on a high speed shaker is described. Using this technique a variety of α‑acylated sugars are prepared, including penta-O-acetyl-α-D-galactopyranose, penta-O-acetyl-α-D-glucopyranose, penta-O-acetyl-α-D-mannopyranose, octa-O-acetyl-α-lactose, penta-O-(3-bromo)benzoyl-α-D-galactopyranose, penta-O-(3-bromo)benzoyl-α-D-gluco-pyranose, penta-O-(3-bromo)benzoyl-α-D-mannopyranose, and octa-O-(3-bromo)benzoyl-α-lactose.

【 授权许可】

Unknown   
© 2005 by MDPI (http://www.mdpi.org).