The tert-Amino Effect in Heterocyclic Chemistry. Synthesis of Spiro Heterocycles

Molecules

Elisaveta V. D’yachenko¹  Tatiana V. Glukhareva¹  Lyudmila V. Dyudya¹  Oleg V. Eltsov¹ 

[1] id="aff-molecules-10-01101">Department of Technology for Organic Synthesis (TOSLab), Urals State Technical University – UPI, 19, Mira str., Ekaterinburg, 620002, Russia. Tel. [phone], Fax: [phone]

关键词: Tert-amino effect;    cyclization;    spiro compounds;    Knoevenagel condensation;    1;    2;    3-thiadiazole;    pyrazole;    quinoline;   

DOI  :  10.3390/10091101

来源: mdpi

【 摘 要 】

The tert-amino reaction effect was examined. A new method to synthesize spiro heterocycles is presented. It was shown that the “tert-amino effect” could be applied to the formation of spiro-fused heterocycles. The formation of spiro compounds proceeds in most cases in good yields in a one-pot reaction.

【 授权许可】

Unknown   
© 2005 by MDPI (http://www.mdpi.org).