New Multi-1,2,3-Selenadiazole Aromatic Derivatives

Molecules

M. Al-Smadi¹ 

[1] Department of Applied Chemical Sciences, Jordan University of Science and Technology, Jordan

关键词: 1;    2;    3-Selenadiazoles;    semicarbazones;    aromatic derivatives;   

DOI  :  10.3390/10091126

来源: mdpi

【 摘 要 】

The aromatic polyketones 3a-d are versatile compounds for the synthesis of the multi-1,2,3-selenadiazole aromatic derivatives 1a-d. The preparation starts with the reaction between the multi-bromomethylene benzene derivatives 2a-d and 4-hydroxy- acetophenone to give compounds 3a-d which are transformed through the reaction with semicarbazide hydrochloride or ethyl hydrazine carboxylate into the corresponding semicarbazones derivatives 4a-d or hydrazones 5a-d. The reaction with selenium dioxide leads to regiospecific ring closure of semicarbazones or hydrazones to give the multi- 1,2,3-selenadiazole aromatic derivatives in high yield.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.