Reactivity of 4-tert-Butyldimethylsiloxy-1,2,3,6-tetrahydro-pyridines with Hydrazines

Molecules

Javier Figueroa²  Esther Caballero¹  Pilar Puebla²  Fernando Tomé² 

[1] id="af1-molecules-11-00929">Química Orgánica y Farmacéutica, Facultad de Farmacia, Campus Miguel de Unamuno, 37007 Salamanca, Spa

关键词: Siloxy-1;    2;    3;    6-tetrahydropyridines;    hydrazones;    pyrazolines;    pyridazinones;   

DOI  :  10.3390/11110929

来源: mdpi

【 摘 要 】

The reactivity of 6-(nitrophenyl or trimethoxyphenyl)-4-tert-butyldimethyl-siloxy-1,2,3,6-tetrahydropyridine derivatives with hydrazines under acid conditions is described. The structure of the products isolated − hydrazones, pyrazolines or pyridazinones − depended on the conditions used. In addition, a systematic study of the reaction outcomes was carried out by introducing variations on the substituents of the tetrahydropyridine ring.

【 授权许可】

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© 2006 by MDPI (http://www.mdpi.org).