Solubilization of Single-walled Carbon Nanotubes with Single-stranded DNA Generated from Asymmetric PCR

International Journal of Molecular Sciences

Zhiqiang Liang¹  Ruojun Lao²  Jing Wang¹  Yongbiao Liu³  Lihua Wang²  Qing Huang²  Shiping Song²  Genxi Li¹ 

[1] Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China; E-mail:;Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, P. R. China; E-mail:;The People’s Hospital of Jiangsu Province, Nanjing 210029, P. R. China

关键词: Carbon nanotubes (CNTs);    single-stranded DNA (ssDNA);    asymmetric PCR;    electrochemical biosensor;   

DOI  :  10.3390/i8070705

来源: mdpi

【 摘 要 】

Carbon nanotubes (CNTs) can be effectively dispersed and functionalized by wrapping with long single-stranded DNA (ssDNA) synthesized by asymmetric PCR. The ssDNA-CNTs attached on surface of glass carbon electrode made it possible for electrochemical analysis and sensing, which was demonstrated by reduction of H₂O₂ on hemoglobin/ssDNA-CNTs modified electrodes. This research showed the potential application of DNA-functionalised CNTs in construction of future electrochemical biosensors.

【 授权许可】

Unknown   
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