International Journal of Molecular Sciences | |
Microwave-Assisted Synthesis of Phenothiazine and Quinoline Derivatives | |
Luiza Găină2  Castelia Cristea2  Claudia Moldovan2  Dan Porumb2  Emanoil Surducan4  Călin Deleanu3  Abdalah Mahamoud1  Jacques Barbe1  | |
[1] Universitée de la Mediteranée, Faculté de Pharmacie, Marseille CEDEX 5, E-mail:;“Babeş-Bolyai” University, Faculty of Chemistry and Chemical Engineering, Organic Chemistry Department, Cluj-Napoca-Ro, E-mail:;Institute of Organic Chemistry, National NMR Laboratory, Bucharest-Ro. E-mail:;INCDTIM-Cluj-Napoca-Ro, E-mail: | |
关键词: MAOS; Quinoline; Pyrido[3; 2-g]quinoline; Phenothiazine; formylation; | |
DOI : 10.3390/i8020070 | |
来源: mdpi | |
【 摘 要 】
Application of a dynamic microwave power system in the chemical synthesis of some phenothiazine and quinoline derivatives is described. Heterocyclic ring formation, aromatic nucleophilic substitution and heterocyclic aldehydes/ketones condensation reactions were performed on solid support, or under solvent free reaction conditions. The microwave-assisted Duff formylation of phenothiazine was achieved. Comparison of microwave-assisted synthesis with the conventional synthetic methods demonstrates advantages related to shorter reaction times and in some cases better reaction yields.
【 授权许可】
Unknown
© 2007 by MDPI
【 预 览 】
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