Structure Elucidation of a Pyrazolo[3,4]pyran Derivative by NMR Spectroscopy

Molecules

Xuehui Liu¹ 

[1] State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100083, P. R. China; E-mail

关键词: NMR;    HMBC;    ⁿJ_CH;    pyrazolo[3;    4]pyran;    proton-deficient compound;   

DOI  :  10.3390/12051117

来源: mdpi

【 摘 要 】

The structure of a representative pyrazolo[3,4]pyran derivative was determined by 1D and 2D NMR techniques. Complete ¹H and ¹³C chemical shifts for this compound are reported. Careful analysis of the HMBC (Heteronuclear Multi-Bond Correlation) spectrum helped to elucidate the configuration of the derivative around C7 and C8. The results showed that the characteristic double-strong and double-weak cross peak pattern in the HMBC spectrum for C7 and C8 might be useful for establishing the structures of other pyrazolo[3,4]pyran derivatives.

【 授权许可】

Unknown   
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