Synthesis and Physical Characterization of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styrylazetidine-2-one as the First β-lactam Bearing a Morpholino Moiety

Molbank

Aliasghar Jarrahpour¹  Abraham F. Jalbout¹ 

[1] ¹epartment of Chemistry, College of Sciences, Shiraz University, Shiraz 71454, Iran ²Department of Chemistry, University of Arizona, Tucson, AZ 85721 USA

关键词: Azetidine-2-one;    N-morpholinopropyl monocyclic β-lactam;    Staudinger reaction;    AM1;   

DOI  :  10.3390/M542

来源: mdpi

【 摘 要 】

In this paper we propose the synthesis of (E)-1-(3-morpholinopropyl)-3-phenoxy-4-styryl azetidine-2-one as a new monocyclic β-lactam. Its structure has been confirmed by IR, 1H-NMR, 13C-NMR and Mass spectroscopic data. In addition to its synthesis we present AM1 calculation to characterize the physical properties of the molecule.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.