A Convenient Synthesis of Amino Acid Methyl Esters

Molecules

Jiabo Li¹ 

[1] The Key Laboratory of Bioorganic Phosphorous Chemistry and Chemical Biology, Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China; E-mail

关键词: Amino acid methyl ester hydrochlorides;    amino acids;    trimethylchlorosilane;    esterification.;   

DOI  :  10.3390/molecules13051111

来源: mdpi

【 摘 要 】

A series of amino acid methyl ester hydrochlorides were prepared in good to excellent yields by the room temperature reaction of amino acids with methanol in the presence of trimethylchlorosilane. This method is not only compatible with natural amino acids, but also with other aromatic and aliphatic amino acids.

【 授权许可】

CC BY   
© 2008 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.