Newly Synthesized Water Soluble Cholinium-Purpurin Photosensitizers and Their Stabilized Gold Nanoparticles as Promising Anticancer Agents

International Journal of Molecular Sciences

Dorjnamjin Demberelnyamba¹  Mama Ariunaa¹ 

[1] id="af1-ijms-09-00864">PDT Research Institute, School of Nano System Engineering, Inje University, Gimhae, South Kor

关键词: Ionic liquid type photosensitizers;    choline;    purpurin-18;    cholinium-purpurin-18;    gold nanoparticles;    anticancer agents;   

DOI  :  10.3390/ijms9050864

来源: mdpi

【 摘 要 】

For possible future use in Photodynamic Therapy (PDT) and/or Photothermal Therapy (PTT) of cancer and screening of cancer cells a new type of ionic liquid photosensitizer –Cholinium-Purpurin-18 (Chol-Pu-18) – was synthesized and small gold (Au) nanoparticles, stabilized by this photosensitizer were prepared without adding any particular reducing agents and CTAB. UV-Vis spectroscopy and Transmission Electron Microscopy (TEM) were used for characterization of the nanoparticles and FAB-MS and NMR of the ionic liquid choline hydroxide, purpurin carboxylate and their ionic liquid type of photosensitizer were obtained.

【 授权许可】

CC BY   
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