Micro Machining of Injection Mold Inserts for Fluidic Channel of Polymeric Biochips

Sensors

Woo-Chul Jung²  Young-Moo Heo²  Gil-Sang Yoon²  Kwang-Ho Shin²  Sung-Ho Chang²  Gun-Hee Kim¹ 

[1] Department of Mechanical Engineering, Inha University, Incheon 402-751, Korea E-mail:;Precision Molds & Dies Team, Incheon R&D Center, KITECH, Incheon 406-840, Korea E-mail:

关键词: Biochip;    lab-on-a-chip;    micro machining;    injection molding;    mold inserts;   

DOI  :  10.3390/s7081643

来源: mdpi

【 摘 要 】

Recently, the polymeric micro-fluidic biochip, often called LOC (lab-on-a-chip), has been focused as a cheap, rapid and simplified method to replace the existing biochemical laboratory works. It becomes possible to form miniaturized lab functionalities on a chip with the development of MEMS technologies. The micro-fluidic chips contain many micro-channels for the flow of sample and reagents, mixing, and detection tasks. Typical substrate materials for the chip are glass and polymers. Typical techniques for microfluidic chip fabrication are utilizing various micro pattern forming methods, such as wet-etching, micro-contact printing, and hot-embossing, micro injection molding, LIGA, and micro powder blasting processes, etc. In this study, to establish the basis of the micro pattern fabrication and mass production of polymeric micro-fluidic chips using injection molding process, micro machining method was applied to form micro-channels on the LOC molds. In the research, a series of machining experiments using micro end-mills were performed to determine optimum machining conditions to improve surface roughness and shape accuracy of designed simplified micro-channels. Obtained conditions were used to machine required mold inserts for micro-channels using micro end-mills. Test injection processes using machined molds and COC polymer were performed, and then the results were investigated.

【 授权许可】

Unknown   
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