Antifouling Metabolites from the Mangrove Plant Ceriops tagal

Molecules

Jun De Chen³  Dan Qin Feng¹  Zhi Wei Yang³  Zhan Chang Wang³  Yan Qiu² 

[1] College of Oceanography and Environmental Science, Xiamen University, Xiamen 361005, P.R. China;Pharmaceutical Department, Medical School, Xiamen University, Xiamen 361005, P. R. China;Department of Biology, School of Life Sciences, Xiamen University, Xiamen 361005, P.R. China

关键词: Diterpenes;    antifouling activity;    barnacle;    Ceriops tagal;   

DOI  :  10.3390/molecules13020212

来源: mdpi

【 摘 要 】

The new diterpene methoxy-ent-8(14)-pimarenely-15-one (1) and three known metabolites: ent-8(14)-pimarene-15R,16-diol (2), stigmasterol (3) and β-sitosterol (4), were isolated from the roots of the mangrove plant Ceriops tagal. Their structures and relative stereochemistry were elucidated by means of extensive NMR, IR and MS analysis. Compounds 1, 2, 3 and 4 exhibited significant antifouling activities against cyprid larvae of the barnacle Balanus albicostatus Pilsbry, with EC₅₀ values of 0.32 ± 0.01, 0.04 ± 0.00, 4.05 ± 0.15 and 18.47 ± 0.40 µg/cm², respectively, whereas their toxicities towards cyprids were very low, with LC₅₀ values all above 10 µg/cm².

【 授权许可】

Unknown   
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