International Journal of Molecular Sciences | |
RNA Interference in Mammalia Cells by RNA-3’-PNA Chimeras | |
Nicoletta Potenza2  Loredana Moggio1  Giovanna Milano1  Vincenzo Salvatore2  Benedetto Di Blasio1  Aniello Russo2  | |
[1] Department of Environmental Sciences, Second University of Naples, Via Vivaldi 43, I-81100 Caserta, Italy; E-mail:;Department of Life Sciences, Second University of Naples, Via Vivaldi 43, I-81100 Caserta, Italy; E-mail: | |
关键词: modified siRNA; RNA interference; RNA-PNA chimeras; Peptide Nucleic Acids; RNA; | |
DOI : 10.3390/ijms9030299 | |
来源: mdpi | |
【 摘 要 】
The discovery of siRNAs as the mediators of RNA interference has led to an increasing interest in their therapeutic applications. Chemical modifications are introduced into siRNAs to optimize the potency, the stability and the pharmacokinetic properties
【 授权许可】
CC BY
© 2008 by MDPI
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