Extraction of Glycyrrhizic Acid and Glabridin from Licorice

International Journal of Molecular Sciences

Minglei Tian¹  Hongyuan Yan¹ 

[1] id="af1-ijms-09-00571">Center for Advanced Bioseperation Technology, Department of Chemical Engineering, Inha University, Incheon 402-751, Kor

关键词: glycyrrhizic acid;    glabridin;    licorice;    extraction;    high-performance liquid chromatography;   

DOI  :  10.3390/ijms9040571

来源: mdpi

【 摘 要 】

The extraction and separation conditions of glycyrrhizic acid and glabridin from licorice were investigated. By changing the different extraction solvents, procedures, times and temperature, the optimum extraction condition was established: the used of ethanol/water (30:70, v/v) as an extraction solvent, and 60 min dipping time under 50°C. The extracts of licorice were separated and determined by reversed-phase high performance liquid chromatography with a methanol/water (70:30, v/v, containing 1% acetic acid) as the mobile phase. Under the optimum extraction condition, 2.39 mg/g of glycyrrhizic acid and 0.92 mg/g of glabridin were extracted from Chinese licorice and the recoveries were 89.7% and 72.5% respectively.

【 授权许可】

CC BY   
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