Complex Etiology, Prophylaxis and Hygiene Control in Mycotoxic Nephropathies in Farm Animals and Humans

International Journal of Molecular Sciences

关键词: mycotoxic nephropathy;    Balkan endemic nephropathy;    ochratoxin A;    penicillic acid;    fumonisin B₁;    synergism;    preventive measures;    hygiene control;    pathogenesis;   

DOI  :  10.3390/ijms9040578

来源: mdpi

【 摘 要 】

Various etiological factors contributing to the development of mycotoxic nephropathy in farm animals and humans are reviewed. The possible synergistic effect between ochratoxin A (OTA) and other mycotoxins, as penicillic acid (PA) and fumonisin B₁ (FB₁), contributing to this nephropathy is also considered and discussed. The most convenient ways of prophylaxis and various preventive measures against OTA contamination of feeds or foods are reviewed. A reference is made concerning the most successful methods of veterinary hygiene control in the slaughterhouses in order to prevent the entering of OTA in commercial channels with a view to human health. The economic efficacy of these prophylactic procedures is also considered. An evaluation of human exposure to OTA is made.

【 授权许可】

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