Efficient and Simple Synthesis of 6-Aryl-1,4-dimethyl-9H-carbazoles

Molecules

Anna Caruso²  Anne Sophie Voisin-Chiret²  Jean-Charles Lancelot²  Maria Stefania Sinicropi¹  Antonio Garofalo¹ 

[1] Università della Calabria, Dipartimento di Scienze Farmaceutiche, 87036 Arcavacata di Rende (CS), Italy;Université de Caen Basse-Normandie, U.F.R. des Sciences Pharmaceutiques, Centre d’Etudes et de Recherche sur le Médicament de Normandie, UPRES EA-4258 FR CNRS INC3M, 5, rue Vaubénard, 14032 Caen Cedex, France

关键词: Carbazole;    ellipticine;    boronic acid;    cross-coupling reaction;   

DOI  :  10.3390/molecules13061312

来源: mdpi

【 摘 要 】

A synthetic method for the preparation of 6-aryl-1,4-dimethyl-9H-carbazoles involving a palladium catalyzed coupling reaction of 1,4-dimethyl-9H-carbazole-6-boronic acids and (hetero)aryl halides is described.

【 授权许可】

CC BY   
© 2008 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.