Survey of Slaughtered Pigs for Occurrence of Ochratoxin A and Porcine Nephropathy in Serbia

International Journal of Molecular Sciences

Dragan Miliၾvić²  Verica Jurić³  Srᄚn Stefanović²  Milijan Jovanović¹ 

[1] Department of Pathomorphology, Faculty of Veterinary Medicine, University of Belgrade, Bulevar Oslobo enja 18, 11000 Beograd, Serbia. E-Mail:;Institute of Meat Hygiene and Technology, Kaćanskog 13, 11000 Belgrade, Serbia;Department for Animal Sciences, Faculty of Agriculture, University of Novi Sad, Trg Dositeja Obradovića 10, 21000 Novi Sad, Serbia. E-Mail:

关键词: Ochratoxin A;    pig;    tissues;    nephropathy;   

DOI  :  10.3390/ijms9112169

来源: mdpi

【 摘 要 】

Samples of blood, kidney and liver were randomly selected from slaughtered pigs (n=90) and analyzed for ochratoxin A by HPLC. In addition, in order to obtain information on the occurrence of nephropathy, histological examinations were carried out. Of the 90 liver samples, 26.6% contained OTA in the range of 0.22–14.5 ng/g. The incidence of OTA in serum and kidney were very similar (31%, 33.3%), with a maximum concentration of 220.8 ng/mL, and 52.5 ng/g, respectively. Histopathological examination of kidneys confirmed tubulopathies with edema and cell vacuolization. In addition, hemorrhages and necrosis of proximal kidney tubules’ cells were found.

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