Novel Strategies to Improve the Anticancer Action of 5-Fluorouracil by Using Drug Delivery Systems

Molecules

关键词: Biodegradable polymers;    Cancer treatment;    Drug carriers;    5-Fluorouracil;    Vesicular systems;   

DOI  :  10.3390/molecules13102340

来源: mdpi

【 摘 要 】

Because of the fundamental importance of new therapeutic routes for cancer treatment, a number of systems based on colloidal particles as vehicles for the delivery of the anticancer drug 5-fluorouracil have been devised. The target is always to provide the proper dose of the antitumor agent only at the desired locus of action, thus reducing the unwanted side effects. In this review, the main strategies and the more significant results in the development of 5-fluorouracil carriers for cancer treatment are discussed.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.