Role of SAM Chain Length in Enhancing the Sensitivity of Nanopillar Modified Electrodes for Glucose Detection

Sensors

Venkataramani Anandan¹  Rajan Gangadharan¹ 

[1] Micro/Nano Bioengineering Lab and

关键词: Gold nanopillar modified electrodes;    self assembled monolayer;    alkanethiols;    electrochemical processes;    glucose detection;    biosensors;   

DOI  :  10.3390/s90301295

来源: mdpi

【 摘 要 】

In this report, alkanethiol self assembled monolayers (SAM) with two different chain lengths were used to immobilize the functionalizing enzyme (glucose oxidase) onto gold nanopillar modified electrodes and the electrochemical processes of these functionalized electrodes in glucose detection were investigated. First, the formation of these SAMs on the nanopillar modified electrodes was characterized by the cyclic voltammetry and electrochemical impedance spectroscopy techniques, and then the detection sensitivity of these functionalized electrodes to glucose was evaluated by the amperometry technique. Results showed that the SAM of alkanethiols with a longer chain length resulted in a higher degree of surface coverage with less defect and a higher electron transfer resistance, whereas the SAM of alkanethiols with a shorter chain length gave rise to a higher detection sensitivity to glucose. This study sheds some new insight into how to enhance the sensing performance of nanopillar modified electrodes.

【 授权许可】

CC BY   
© 2009 by the authors; licensee MDPI, Basel, Switzerland