Thiopental and Phenytoin as Novel Ionophores for Potentiometric Determination of Lead (II) Ions

Sensors

Nashwa M.H. Rizk²  Samah S. Abbas³  Salem M. Hamza¹ 

[1] Chemistry Department, Faculty of Sciences, Minufiya University, Egypt E-mail:;Environmental Biotechnology Department, Genetic Engineering and Biotechnology Research Institute (GEBRI), Minufiya University, Sadat City, Egypt;Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, Egypt; E-mail:

关键词: Lead (II);    Thiopental;    Phenytoin;    Galena rocks;    Solder alloys;   

DOI  :  10.3390/s90301860

来源: mdpi

【 摘 要 】

Two novel polymeric membrane sensors for the analysis of Pb(II) have been developed based on two therapeutic drugs, thiopental (TP) and phenytoin (PT) as two new ionophores and potassium tetrakis(p-chlorophenyl) borate (KTpClPB) as a lipophilic additive, in plasticized PVC membranes. The sensors show a Nernstian response for Pb(II) ions over the wide concentration ranges of 1×10⁻² – 7×10⁻⁶ M and 1×10⁻² – 8×10⁻⁶ M for the sensors based on thiopental and phenytoin, respectively. The proposed sensors have a fast response time and can be used for more than nine weeks without any considerable divergence in potentials. The sensors exhibit comparatively good selectivity with respect to alkaline, alkaline earth and some transition and heavy metal ions. They were employed for direct determination of lead in solder alloys and in galena rocks with a good agreement with the obtained results by atomic absorption spectroscopy.

【 授权许可】

CC BY   
© 2009 by the authors; licensee MDPI, Basel, Switzerland