Rubiacordone A: A New Anthraquinone Glycoside from the Roots of Rubia cordifolia

Molecules

Xiang Li²  Zhi Liu¹  Yun Chen³  Li-Juan Wang²  Yi-Nan Zheng²  Guang-Zhi Sun¹ 

[1] Institute of Agricultural Modernization, Jilin Agricultural University, Changchun, 130118, P.R. China; E-mails:;College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun, 130118, P.R. China; E-mails:;Research Centre for Medical and Structural Biology, School of Basic Medical Science, Wuhan University, Wuhan, 430071, P.R. China; E-mail:

关键词: Rubia cordifolia;    Rubiacordone A;    Anthraquinone;    Antimicrobial.;   

DOI  :  10.3390/molecules14010566

来源: mdpi

【 摘 要 】

A new anthraquinone, Rubiacordone A (1) (6-acetoxy-1-hydroxy-2-methylanthraquinone-3-O-α-l-rhamnopyranoside), was isolated together with the known anthraquinone, 1-acetoxy-6-hydroxy-2-methylanthraquinone-3-O-[α-l-rhamnopyranosyl-(1→2)-β-d-glucopyranoside] (2), from the dried roots of Rubia cordifolia. Their structures were elucidated on the basis of extensive 1D and 2D-NMR, as well as HRESI-MS spectroscopic analysis. Metabolites 1 and 2 showed considerable antimicrobial activity against Gram-positive bacteria.

【 授权许可】

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© 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.