Determination of Proton Relaxivities of Mn(II), Cu(II) and Cr(III) added to Solutions of Serum Proteins

Molecules

Mehmet Zafer Köylü¹  Sezai Asubay² 

[1] id="af1-molecules-14-01537">Department of Physics, University of Dicle, 21280 Diyarbakir, Turke

关键词: MRI;    T₁;    T₂;    Mn(II);    Cu(II);    Cr(III);    Serum proteins.;   

DOI  :  10.3390/molecules14041537

来源: mdpi

【 摘 要 】

Relaxometric studies are still of scientific interest due to their use in medicine and biology. In this study, proton T₁ and T₂ relaxivities of Mn(II), Cu(II) and Cr(III) in water were determined in the presence and absence of various proteins (albumin, α-globulin, γ-globulin, lysozyme, fibrinogen). The 1/T₁ and 1/T₂ in all solutions are linearly proportional to the concentration of the paramagnetic ions. Mn(II) has the great influence to alter relaxations in all protein solutions, while Cu(II) and Cr(III) have a poor influence on the relaxations. In addition, Mn(II) and Cu(II) are bound to each protein, but Cr(III) is not bound to any protein.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.