Antibody-Based Sensors: Principles, Problems and Potential for Detection of Pathogens and Associated Toxins

Sensors

Barry Byrne¹  Edwina Stack²  Niamh Gilmartin² 

[1] Centre for Bioanalytical Sciences (CBAS), Dublin City University, Dublin 9, Ireland; E-Mail:;National Centre for Sensor Research (NCSR), Dublin City University, Dublin 9, Ireland; E-Mails:

关键词: pathogen;    antibody;    biosensor;    electrochemical;    surface-plasmon resonance;    assay development;   

DOI  :  10.3390/s90604407

来源: mdpi

【 摘 要 】

Antibody-based sensors permit the rapid and sensitive analysis of a range of pathogens and associated toxins. A critical assessment of the implementation of such formats is provided, with reference to their principles, problems and potential for ‘on-site’ analysis. Particular emphasis is placed on the detection of foodborne bacterial pathogens, such as Escherichia coli and Listeria monocytogenes, and additional examples relating to the monitoring of fungal pathogens, viruses, mycotoxins, marine toxins and parasites are also provided.

【 授权许可】

CC BY   
© 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.