Iodoarylation of Arylalkynes with Molecular Iodine in the Presence of Hypervalent Iodine Reagents

Molecules

Md. Ataur Rahman¹ 

[1] Department of Chemistry and Applied Chemistry, Faculty of Science and Engineering, Saga University, Honjo-machi, Saga, 840-8502, Japan

关键词: iodoarylation;    alkyne;    molecular iodine;    hypervalent iodine;    iodoethene;   

DOI  :  10.3390/molecules14093132

来源: mdpi

【 摘 要 】

Iodoarylation of arylacetylenes was performed using a simple reagent system composed of molecular iodine and [bis(benzoyloxy)iodo]benzene. Most arylacetylenes efficiently underwent the iodoarylation reaction with electron-rich arenes to give trans 1,1-diaryl-2-iodoethene adducts regio- and stereoselectively. As an exception, the iodoarylation of p-methoxyphenylacetylene resulted in a mixture of E- and Z-isomers of the corresponding product.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.