Epidemiological Study of Rickettsial Infections in Patients with Hypertransaminemia in Madrid (Spain)

International Journal of Environmental Research and Public Health

Lourdes Lledó¹  Rosario González¹  Mar໚ Isabel Gegúndez¹  Mar໚ Beltrán¹ 

[1] Department of Microbiology and Parasitology, Faculty of Medicine, University of Alcalá, Ctra. Madrid-Barcelona Km 33.6, Alcalá de Henares 28871, Spain; E-Mails:

关键词: Rickettsiae;    hypertransaminemia;    liver dysfunction;    prevalence;    Spain;   

DOI  :  10.3390/ijerph6102526

来源: mdpi

【 摘 要 】

A retrospective analysis was performed to detect anti-rickettsial antibodies in the serum of patients with hypertransaminemia of unknown etiology, and in that of healthy members of the general population of Madrid (Spain). Among 143 patients 16 (11.2%) were positive for anti-R. conorii IgG antibodies and 7% for R. typhi. PCR analysis was performed in patients with IgM antibodies. Among 143 healthy subjects from the general population, seven (4.9%) were positive for anti-R. conorii IgG antibodies, and 2.8% for R. typhi. These results show that anti-rickettsial antibodies are more commonly detected in patients with hypertransaminemia than in healthy people.

【 授权许可】

CC BY   
© 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.