International Journal of Molecular Sciences | |
Robustness in Regulatory Interaction Networks. A Generic Approach with Applications at Different Levels: Physiologic, Metabolic and Genetic | |
Jacques Demongeot1  Hedi Ben Amor1  Adrien Elena1  Pierre Gillois1  Mathilde Noual2  | |
[1] Université J. Fourier de Grenoble, TIMC-IMAG, CNRS UMR 5525, Faculté de Médecine, 38700 La Tronche, France; E-Mails:;Université de Lyon, École Normale Supérieure Lyon, LIP, CNRS UMR 5668, 69007 Lyon, France | |
关键词: robustness in regulatory interaction networks; attractors; interaction graph boundary; interaction graph core; critical node; critical edge; updating mode; microRNAs; | |
DOI : 10.3390/ijms10104437 | |
来源: mdpi | |
【 摘 要 】
Regulatory interaction networks are often studied on their dynamical side (existence of attractors, study of their stability). We focus here also on their robustness, that is their ability to offer the same spatiotemporal patterns and to resist to external perturbations such as losses of nodes or edges in the networks interactions architecture, changes in their environmental boundary conditions as well as changes in the update schedule (or updating mode) of the states of their elements (
【 授权许可】
CC BY
© 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190055948ZK.pdf | 2015KB | download |