Tiny Medicine: Nanomaterial-Based Biosensors

Sensors

Yeo-Heung Yun¹  Edward Eteshola⁴  Amit Bhattacharya³  Zhongyun Dong⁵  Joon-Sub Shim⁶  Laura Conforti⁵  Dogyoon Kim²  Mark J. Schulz¹  Chong H. Ahn⁶ 

[1] Nanoworld and Smart Materials and Devices Laboratory, College of Engineering, University of Cincinnati, OH, 45221, USA; E-Mail:;College of Dentistry, The Ohio State University, OH, 43210, USA; E-Mail:;Environmental Health, College of Medicine, University of Cincinnati, OH, 45267, USA; E-Mail:;Davis Heart & Lung Research Inst, Biomedical Engineering Dept. The Ohio State University, OH, 43210, USA; E-Mail:;Internal Medicine, College of Medicine, University of Cincinnati, OH, 45221, USA; E-Mail:;BioMEMS Lab, College of Engineering, University of Cincinnati, OH, 45221, USA; E-Mail:

关键词: tiny medicine;    nanomaterials;    point of care;   

DOI  :  10.3390/s91109275

来源: mdpi

【 摘 要 】

Tiny medicine refers to the development of small easy to use devices that can help in the early diagnosis and treatment of disease. Early diagnosis is the key to successfully treating many diseases. Nanomaterial-based biosensors utilize the unique properties of biological and physical nanomaterials to recognize a target molecule and effect transduction of an electronic signal. In general, the advantages of nanomaterial-based biosensors are fast response, small size, high sensitivity, and portability compared to existing large electrodes and sensors. Systems integration is the core technology that enables tiny medicine. Integration of nanomaterials, microfluidics, automatic samplers, and transduction devices on a single chip provides many advantages for point of care devices such as biosensors. Biosensors are also being used as new analytical tools to study medicine. Thus this paper reviews how nanomaterials can be used to build biosensors and how these biosensors can help now and in the future to detect disease and monitor therapies.

【 授权许可】

CC BY   
© 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.