Chemical Constituents from Clematis delavayi var. spinescens

Molecules

Yang Li¹  Si-Feng Wang¹  Yan-Li Zhao¹  Ke-Chun Liu¹  Xi-Min Wang¹  Yong-Ping Yang¹ 

[1] ¹Laboratory of Ethnobotany, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China ²Institute of Tibetan Plateau Research at Kunming, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, China ³Biology Institute of Shandong Academy of Sciences, Jinan 250014, Shandong, China

关键词: coumarin;    Clematis delavayi var. spinescens;    NMR;    antiangiogenic effects;   

DOI  :  10.3390/molecules14114433

来源: mdpi

【 摘 要 】

A new coumarin, 7-hydroxy-4,6-dimethoxy-5-methylcoumarin (1), was isolated from the aerial parts of Clematis delavayi var. spinescens together with 17 known compounds. Their structures were identified by extensive spectral analysis, especially 2D NMR techniques. Antiangiogenic effects of all compounds were evaluated using a zebrafish model.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.