Impact of Co-Occurring Psychiatric Disorders on Retention in a Methadone Maintenance Program: An 18-Month Follow-Up Study

International Journal of Environmental Research and Public Health

Mònica Astals²  Laura D໚z²  Antònia Domingo-Salvany¹  Rocío Martín-Santos²  Antoni Bulbena² 

[1] Research Programme in Epidemiology and Public Health, Institut Municipal d’Investigació Medica (IMIM), Hospital del Mar, Doctor Aiguader 88, E-08003 Barcelona, Spain; E-Mail:;Institute of Psychiatry and Addiction (IAPs), Hospital del Mar and Institut Municipal d’Investigació Mèdica (IMIM), Hospital del Mar, Psg. Marítim 25-29, E-08003 Barcelona, Spain; E-Mails:

关键词: methadone;    retention;    co-occurring psychiatric disorders;    incidence;   

DOI  :  10.3390/ijerph6112822

来源: mdpi

【 摘 要 】

We assess the influence of co-occurring psychiatric disorders on retention in 189 opioid dependent patients in a methadone maintenance treatment (MMT) and determine the incidence of psychiatric co-morbidity during an 18-month follow-up period. About 68.5 % were retained in the MMT. Neither co-occurring mental disorders (chi-square = 0.303, df = 1, p = 0.622) nor methadone doses [85 (88.9) vs. 79.2 (85) mg/day, p = 0.672] were related to retention. In the follow-up period 19 new diagnoses were made, mainly major depression and antisocial and borderline personality disorders. Co-occurring psychiatric disorders should be assessed during MMT follow-up.

【 授权许可】

CC BY   
© 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.