Hypersensitivity Reactions to Nonsteroidal Anti-Inflammatory Drugs: An Update

Pharmaceuticals

Mario Sánchez-Borges¹  Fernan Caballero-Fonseca¹  Arnaldo Capriles-Hulett¹ 

[1] Allergy and Immunology Department, Centro Médico Docente La Trinidad, Caracas, Venezuela; E-Mails:

关键词: asthma;    anaphylaxis;    drug reactions;    non steroidal anti-inflammatory drugs (NSAIDs);    urticaria and angioedema;   

DOI  :  10.3390/ph3010010

来源: mdpi

【 摘 要 】

After beta lactam antibiotics, hypersensitivity reactions to nonsteroidal anti-inflammatory drugs are the second cause of hypersensitivity to drugs. Acute manifestations affect the respiratory tract (aspirin exacerbated respiratory disease), the skin (urticaria and angioedema), or are generalized (anaphylaxis). Correct diagnosis and treatment in order to prevent unnecessary morbidity and the potential risk of death from these severe reactions, and to provide proper medical advice on future drug use frequently requires the participation of allergology specialists familiar with these clinical conditions.

【 授权许可】

CC BY   
© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.