Comparison of Locoregional Recurrence with Mastectomy vs. Breast Conserving Surgery in Pregnancy Associated Breast Cancer (PABC)

Cancers

Sushil Beriwal²  Bunja Rungruang³  Atilla Soran¹  Darcy Thull⁶  Joseph L. Kelley³  Rohit Bhargava⁴  Chyongchiou J. Lin⁵ 

[1] Department of Surgery, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USA; E-Mail:;Department of Radiation Oncology, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USA; E-Mail:;Department of Gynecologic Oncology, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USA; E-Mails:;Department of Pathology, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USA; E-Mail:;Department of Family Medicine, School of Medicine, University of Pittsburgh, 3518 Fifth Avenue, Pittsburgh, PA 15261, USA; E-Mail:;Division of Hematology Oncology, Magee-Womens Hospital of UPMC, 300 Halket Street, Pittsburgh, PA 15213, USA; E-Mail:

关键词: pregnancy;    cancer;    surgery;    mastectomy;    breast conserving surgery;   

DOI  :  10.3390/cancers1010012

来源: mdpi

【 摘 要 】

We have compared outcomes, including the locoregional recurrence, between mastectomy and breast conserving therapy in PABC. Patients were divided into those who were treated with mastectomies (group 1) and those with breast conserving surgery (group 2). The groups were comparable except for lower mean age in group 2 and more patients with stage III disease and higher number of nodes positive in the group 1. Five-year actuarial LRR, distant metastases free survival and overall survival in group 1 vs. 2 were 10% vs. 37%, 73% vs. 81% and 57% vs. 59% respectively. The patients with PABC treated with breast conserving therapy, despite having lower stage disease, have a higher risk of local regional recurrence in comparison with those treated with mastectomy.

【 授权许可】

CC BY   
© 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.